The problem is with the overall concept of the play and, indeed, of Shakespearean tragic plays in general. Most of them hinge on debilitating flaws in their protagonists' insight Othello's jealousy, Hamlet's hesitance or Macbeth's uxoriousness that bring them down. Antony and Cleopatra are grownups with grownup responsibilities: the former for holding Rome together as it moves from republic to empire; the latter guarding the rights of her people against Rome. Neither Chopper Leifheit, who plays Antony, nor Donna M. Parroné, the production's Cleopatra, comes across as a leader of a nation. Leifheit is never convincing as a general, nor is Parroné as a queen.
This is a director's problem, not the actors'. Donna Northcott has Antony's men treat him as one of the boys, and Cleopatra's attendants never give her the deference due a queen. Why should we care about their fates if they don't? Northcott does move things along, however, and the production is never dull.